abstract：INTRODUCTION:Root canal therapy is a highly successful in-office treatment and preventive measure against periapical abscesses. Left untreated, periapical abscesses can have serious consequences that can lead to hospitalization. This study observes the trends of hospitalizations attributed to periapical abscesses. MET...

journal_title：Journal of endodontics

authors： Shah AC,Leong KK,Lee MK,Allareddy V

更新日期：2013-09-01 00:00:00

abstract：INTRODUCTION:Cell migration is an important step in pulpal wound healing. Although components in the resin-based dental materials are known to have adverse effects on pulp wound healing including proliferation and mineralization, their effects on cell migration have been scarcely examined. Here, we investigated the eff...

journal_title：Journal of endodontics

authors： Williams DW,Wu H,Oh JE,Fakhar C,Kang MK,Shin KH,Park NH,Kim RH

更新日期：2013-09-01 00:00:00

abstract：INTRODUCTION:The purpose of this retrospective study was to determine the success of the inferior alveolar nerve (IAN) block using either 3.6 mL or 1.8 mL 2% lidocaine with 1:100,000 epinephrine in patients presenting with symptomatic irreversible pulpitis. METHODS:As part of 7 previously published studies, 319 emerge...

journal_title：Journal of endodontics

authors： Fowler S,Reader A

更新日期：2013-08-01 00:00:00

abstract：INTRODUCTION:The aim of this study was to investigate the role of the extracellular signal-regulated kinase 1/2 (ERK1/2) pathway in regulating tricalcium silicate (C3S)-driven proliferation and biomineralization of human dental pulp cells (hDPCs) in vitro. METHODS:Human DPCs were cultured in C3S-containing medium and ...

journal_title：Journal of endodontics

authors： Du R,Wu T,Liu W,Li L,Jiang L,Peng W,Chang J,Zhu Y

更新日期：2013-08-01 00:00:00

abstract：INTRODUCTION:The purpose of this study was to compare the ability of MTA (Dentsply Maillefer, Tulsa, OK) and EndoSequence Root Repair Material (ESRRM; Brasseler USA, Savannah, GA) to set in the presence of human blood and minimal essential media. METHODS:A model was created using polymethyl methacrylate blocks each pr...

journal_title：Journal of endodontics

authors： Charland T,Hartwell GR,Hirschberg C,Patel R

更新日期：2013-08-01 00:00:00

abstract：INTRODUCTION:The aim of this study was to analyze and characterize root canal morphology of mandibular molars of the Brazilian population by using cone-beam computed tomography (CBCT). METHODS:Patients who required CBCT radiographic examinations as part of their routine examination, diagnosis, and treatment planning w...

journal_title：Journal of endodontics

authors： Silva EJ,Nejaim Y,Silva AV,Haiter-Neto F,Cohenca N

更新日期：2013-07-01 00:00:00

abstract：INTRODUCTION:The purpose of this study was to compare digital periapical and cone-beam computed tomography (CBCT) images to determine the number of canals in the mesiobuccal root of maxillary molars and to compare these counts with micro computed tomography (μCT), which was also used to determine canal configuration. ...

journal_title：Journal of endodontics

authors： Domark JD,Hatton JF,Benison RP,Hildebolt CF

更新日期：2013-07-01 00:00:00

abstract：INTRODUCTION:The aim of this study was to examine the effect of pulp cell injection on host angiogenesis during wound healing. METHODS:Pulp cells were isolated from extracted premolars by the outgrowth method. Fluorescently labeled pulp cells or phosphate-buffered saline were locally injected into a mouse wound healin...

journal_title：Journal of endodontics

authors： Yang H,Shin S,Ahn J,Choi Y,Kim KH,Chung CJ

更新日期：2013-06-01 00:00:00

abstract：INTRODUCTION:The aim of this study was to investigate the potential of autologous mesenchymal bone marrow stem cells (BMSCs) to promote hard-tissue formation after direct pulp capping procedures. MATERIALS AND METHODS:Bone marrow was aspirated from the iliac crest of healthy dogs of nonspecific race. Mononuclear cells...

journal_title：Journal of endodontics

authors： Obeid M,Saber Sel D,Ismael Ael D,Hassanien E

更新日期：2013-05-01 00:00:00

abstract：INTRODUCTION:Fractured endodontic files present a major problem. A novel method has been proposed to retrieve fractured nickel-titanium (NiTi) endodontic files by using electrochemical dissolution. However, the effect of file dissolution on adjacent soft tissues such as the periodontal ligament (PDL) has not been inves...

journal_title：Journal of endodontics

authors： Mitchell Q,Jeansonne BG,Stoute D,Lallier TE

更新日期：2013-05-01 00:00:00

abstract：INTRODUCTION:Phentolamine mesylate has been reported to be an effective local anesthetic reversal agent for soft tissue but has not been studied regarding reversal of pulpal anesthesia. The authors conducted a prospective randomized, single-blind study comparing the reversal of pulpal and soft tissue anesthesia when ph...

journal_title：Journal of endodontics

authors： Elmore S,Nusstein J,Drum M,Reader A,Beck M,Fowler S

更新日期：2013-04-01 00:00:00

abstract：INTRODUCTION:This study examined the effect of a new bioactive dentin substitute material (Biodentine) on the viability of human gingival fibroblasts. METHODS:Biodentine, White ProRoot mineral trioxide aggregate (MTA), and glass ionomer cement were evaluated. Human gingival fibroblasts were incubated for 1, 3, and 7 d...

journal_title：Journal of endodontics

authors： Zhou HM,Shen Y,Wang ZJ,Li L,Zheng YF,Häkkinen L,Haapasalo M

更新日期：2013-04-01 00:00:00

abstract：INTRODUCTION:Difficult handling, long setting time, and potential discoloration are important drawbacks of white mineral trioxide aggregate (WMTA). The development of Biodentine, a recently developed calcium silicate-based material (CSM), has overcome some of these shortcomings; however, there are no available data on ...

journal_title：Journal of endodontics

authors： Vallés M,Mercadé M,Duran-Sindreu F,Bourdelande JL,Roig M

更新日期：2013-04-01 00:00:00

abstract：INTRODUCTION:The authors conducted a prospective, randomized, single-blind study to determine the degree of pulpal anesthesia obtained with a primary infiltration of 1 cartridge of articaine in the incisive/mental nerve region of the mandibular second premolar and to determine the anesthetic efficacy of a repeat artica...

journal_title：Journal of endodontics

authors： Dressman AS,Nusstein J,Drum M,Reader A

更新日期：2013-03-01 00:00:00

abstract：INTRODUCTION:This study evaluated the risk of failure for an endodontically treated premolar with different crack depths, which was shearing toward the pulp chamber and was restored by using 3 different computer-aided design/computer-aided manufacturing ceramic restoration configurations. METHODS:Three 3-dimensional f...

journal_title：Journal of endodontics

authors： Lin CL,Chang YH,Hsieh SK,Chang WJ

更新日期：2013-03-01 00:00:00

abstract：INTRODUCTION:Pulp revascularization may be considered a promising alternative for necrotic immature teeth. Many studies have accomplished passive decontamination associated with an antibiotic paste. To date, there is no report evaluating calcium hydroxide associated with 2% chlorhexidine gel for revascularization thera...

journal_title：Journal of endodontics

authors： Soares Ade J,Lins FF,Nagata JY,Gomes BP,Zaia AA,Ferraz CC,de Almeida JF,de Souza-Filho FJ

更新日期：2013-03-01 00:00:00

abstract：:The oral region comprises 1% of the total body area, yet it accounts for 5% of all bodily injuries. In preschool children, oral injuries make up as much as 17% of all bodily injuries. The incidence of traumatic dental injuries is 1%-3%, and the prevalence is steady at 20%-30%. The annual cost of treatment is US $2-$5 ...

journal_title：Journal of endodontics

authors： Andersson L

更新日期：2013-03-01 00:00:00

abstract：:This review considers oral trauma and its relationship to orthodontics with respect to prevention and primary, secondary, and tertiary care. The level of evidence is not high in regard to this topic, but recommendable approaches to trauma at each stage are discussed on the basis of available literature and published g...

journal_title：Journal of endodontics

authors： Fields HW,Christensen JR

更新日期：2013-03-01 00:00:00

abstract：INTRODUCTION:The health of human teeth depends on the integrity of the hard tissue and the activity of the pulp and periodontal tissues, which are responsible for nutritional supply. Without the nourishing of the pulp tissue, the possibility of tooth fracture can increase. In immature permanent teeth, root development ...

journal_title：Journal of endodontics

authors： Wang Y,Zhao Y,Jia W,Yang J,Ge L

更新日期：2013-02-01 00:00:00

abstract：INTRODUCTION:The aim of the present study was to assess the bond strength of root fillings in oval-shaped canals prepared with the self-adjusting file (SAF) system. METHODS:A careful specimen selection resulted in 2 equal groups, each consisting of 12 extracted mandibular canines with oval canals that had vital pulps ...

journal_title：Journal of endodontics

authors： De-Deus G,Accorsi-Mendonça T,de Carvalho e Silva L,Leite CA,da Silva D,Moreira EJ

更新日期：2013-02-01 00:00:00

abstract：INTRODUCTION:The aim of this study was to compare the fracture resistance of cast posts versus the fracture resistance of fiber posts by means of meta-analysis when they were used in the restoration of endodontically treated teeth. METHODS:MEDLINE, Cochrane Controlled Trials Register, China National Knowledge Infrastr...

journal_title：Journal of endodontics

authors： Zhou L,Wang Q

更新日期：2013-01-01 00:00:00

abstract：INTRODUCTION:The purpose of this study was to examine the effect of mineral trioxide aggregate (MTA) on pluripotent-mesenchymal cell differentiation. METHODS:The pluripotent-mesenchymal cell line C2C12 was cultured in a 5% serum medium to induce cell differentiation with or without MTA. The differentiation to myoblast...

journal_title：Journal of endodontics

authors： Matsumoto S,Hayashi M,Suzuki Y,Suzuki N,Maeno M,Ogiso B

更新日期：2013-01-01 00:00:00

abstract：INTRODUCTION:The purpose of this investigation was to determine the effect that apical preparation size and preparation taper have on the volume of irrigant delivered at the working length for different canal curvatures using apical negative pressure irrigation. METHODS:One hundred fifty-five human teeth (55 maxillary...

journal_title：Journal of endodontics

authors： de Gregorio C,Arias A,Navarrete N,Del Rio V,Oltra E,Cohenca N

更新日期：2013-01-01 00:00:00

abstract：INTRODUCTION:Speed of injection may affect the solution spread in the pterygomandibular space. It was hypothesized that speed of injection will affect the anesthetic efficacy of inferior alveolar nerve block (IANB) in patients with symptomatic irreversible pulpitis. METHODS:Fifty-nine adult volunteers who were activel...

journal_title：Journal of endodontics

authors： Aggarwal V,Singla M,Miglani S,Kohli S,Irfan M

更新日期：2012-12-01 00:00:00

abstract：INTRODUCTION:Various materials have been advocated for use as root-end filling materials. The purpose of the present in vitro study was to compare the cytotoxicity of 4 root-end filling materials: glass ionomer cement (GIC; Fuji II, GC Corp, Tokyo, Japan), reinforced zinc oxide-eugenol cement (IRM; Dentsply Tulsa Denta...

journal_title：Journal of endodontics

authors： Lee BN,Son HJ,Noh HJ,Koh JT,Chang HS,Hwang IN,Hwang YC,Oh WM

更新日期：2012-12-01 00:00:00

abstract：INTRODUCTION:This article reports on the feasibility of conducting a large-scale endodontic prospective cohort study in The National Dental Practice-Based Research Network. This study was designed to measure pain and burden associated with initial orthograde root canal therapy (RCT) and to explore potential prognostic ...

journal_title：Journal of endodontics

authors： Nixdorf DR,Law AS,Look JO,Rindal DB,Durand EU,Kang W,Agee BS,Fellows JL,Gordan VV,Gilbert GH,National Dental PBRN Collaborative Group.

更新日期：2012-11-01 00:00:00

abstract：INTRODUCTION:Irrigation dynamics and antibacterial activity determine the efficacy of root canal disinfection. Sonic or ultrasonic agitation of irrigants is expected to improve irrigation dynamics. This study examined the effects of microbubble emulsion (ME) combined with sonic or ultrasonic agitation on irrigation dyn...

journal_title：Journal of endodontics

authors： Halford A,Ohl CD,Azarpazhooh A,Basrani B,Friedman S,Kishen A

更新日期：2012-11-01 00:00:00

abstract：INTRODUCTION:Patient preferences should be taken into account by clinicians when treatment planning. The purposes of this study were to describe the number of visits patients preferred when undergoing root canal therapy (RCT) and to assess whether their preferences were related to hypothetical treatment success rates. ...

journal_title：Journal of endodontics

authors： Vela KC,Walton RE,Trope M,Windschitl P,Caplan DJ

更新日期：2012-10-01 00:00:00

abstract：INTRODUCTION:Regenerative endodontic procedures are an alternative treatment for immature teeth with necrotic pulps. Typically, intracanal medicaments such as triple antibiotic paste (TAP) or double antibiotic paste (DAP) and calcium hydroxide (Ca[OH](2)) are used for disinfection. However, their effect on human stem c...

journal_title：Journal of endodontics

authors： Ruparel NB,Teixeira FB,Ferraz CC,Diogenes A

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:The aim of this in vitro study was to evaluate the depth of penetration of 4 different endodontic resin sealers into the radicular dentinal tubules with the aid of confocal microscopy. METHODS:Eighty single-rooted teeth were instrumented and divided into 4 groups composed of 20 teeth each. The samples were ...

journal_title：Journal of endodontics

authors： Chandra SS,Shankar P,Indira R

更新日期：2012-10-01 00:00:00

abstract：INTRODUCTION:Cross-sectional studies describe the health status of a population and measure the prevalence of disease or treatment. Neither the prevalence of periapical radiolucency, a surrogate for disease, nor the prevalence of root canal treatment have been subjected to a systematic review, which is the highest leve...

journal_title：Journal of endodontics

authors： Pak JG,Fayazi S,White SN

更新日期：2012-09-01 00:00:00

abstract：INTRODUCTION:Collagen dentin matrix may represent a suitable scaffold to be remineralized in the presence of bioactive materials. The purpose of this study was to determine if experimental resin cements containing bioactive fillers may modulate matrix metalloproteinase-mediated collagen degradation of etched dentin. M...

journal_title：Journal of endodontics

authors： Osorio R,Yamauti M,Sauro S,Watson TF,Toledano M

更新日期：2012-09-01 00:00:00

abstract：INTRODUCTION:Newer antibacterial alternatives such as chitosan nanoparticles (CSnps) and photodynamic therapy (PDT) have been investigated to achieve effective root canal disinfection. The current study aims to assess the effect of various tissue inhibitors such as dentin, dentin matrix, pulp tissue, bacterial lipopoly...

journal_title：Journal of endodontics

authors： Shrestha A,Kishen A

更新日期：2012-09-01 00:00:00

abstract：INTRODUCTION:This clinical study was conducted to compare the levels of endotoxins (lipopolysaccharides [LPSs]) found in primary and secondary endodontic infections with apical periodontitis by correlating LPS contents with clinical/radiographic findings. In addition, the presence of target gram-negative anaerobic bact...

journal_title：Journal of endodontics

authors： Gomes BP,Endo MS,Martinho FC

更新日期：2012-08-01 00:00:00

abstract：INTRODUCTION:Mineral trioxide aggregate (MTA) has been used successfully for perforation repair, vital pulpotomies, and direct pulp capping. However, little is known about the interactions between MTA and glass ionomer cement (GIC) in final restorations. In this study, 2 null hypotheses were tested: (1) GIC placement t...

journal_title：Journal of endodontics

authors： Eid AA,Komabayashi T,Watanabe E,Shiraishi T,Watanabe I

更新日期：2012-08-01 00:00:00

abstract：INTRODUCTION:Enterococcus faecalis is frequently recovered from root-filled teeth with refractory apical periodontitis. The ability of E. faecalis to form a matrix-encased biofilm contributes to its pathogenicity; however, the role of extracellular dextran and DNA in biofilm formation and its effect on the susceptibili...

journal_title：Journal of endodontics

authors： Li W,Liu H,Xu Q

更新日期：2012-07-01 00:00:00

abstract：INTRODUCTION:Microorganisms are able to survive and cause persistent infection in the extraradicular area. The aims of this study were to investigate the primary bacterial flora and the localization of extraradicular biofilm in persistent apical periodontitis lesions. METHODS:Apical root samples from root-end surgery ...

journal_title：Journal of endodontics

authors： Wang J,Jiang Y,Chen W,Zhu C,Liang J

更新日期：2012-07-01 00:00:00

abstract：INTRODUCTION:Mineral trioxide aggregate (MTA) satisfies most of the ideal properties of a surgical root-end filling and perforation repair material. It has been found to be nontoxic, noncarcinogenic, nongenotoxic, biocompatible, insoluble in tissue fluids, and dimensionally stable and promotes cementogenesis. The major...

journal_title：Journal of endodontics

authors： Appelbaum KS,Stewart JT,Hartwell GR

更新日期：2012-07-01 00:00:00

abstract：INTRODUCTION:The lysyl oxidase (LOX) family is an emerging family of amine oxidases responsible for the formation of collagen fibrils in the extracellular matrix. To date, 5 LOX family genes have been identified in humans, encoding LOX and LOX-like proteins (LOXL, LOXL2, LOXL3, and LOXL4). The goal of this study was to...

journal_title：Journal of endodontics

authors： Kim EC,Lee HJ,Kim Y

更新日期：2012-06-01 00:00:00

abstract：INTRODUCTION:Calcium silicate-based materials (CSMs) are used in various endodontic procedures. The present study examined whether prolonged contact of mineralized dentin with recently commercialized versions of these materials adversely affects dentin collagen matrix integrity. METHODS:Dentin slabs prepared from extr...

journal_title：Journal of endodontics

authors： Leiendecker AP,Qi YP,Sawyer AN,Niu LN,Agee KA,Loushine RJ,Weller RN,Pashley DH,Tay FR

更新日期：2012-06-01 00:00:00